Week 1
This week you will learn foundational concepts about the structure and function of the human genome and different types of genetic and non-genetic variation that occur.
Week 2
This week, Drs. Nussbaum and Norton will describe the use of genomics in the reproductive setting: carrier testing, non-invasive prenatal screening, prenatal diagnosis of Mendelian diseases, and newborn screening.
Week 3
This week Dr. Nussbaum will review the use of next-generation sequencing for solving diagnostic dilemmas.
Week 4
This week we will explore the genetics of common, complex diseases and the population genetics methods used to uncover genetic associations.
Week 5
This week Dr. Mendelsohn joins me to roll play some scenarios to teach you about predictive tests for common, complex diseases and direct-to-consumer testing.
Week 6
This week we discuss pharmacogenomic testing for drug selection, dosing and predicting adverse effects of commonly prescribed drugs.
Week 7
Our final lecture explores tumor profiling for targeting cancer treatment and the use of blood-based gene expression profiles in cancer prognosis.
