Organic Chemistry 1

Por: Swayam . en: , ,

Overview

This course is a 4 credit course (15 weeks, 40 module) for M. Sc. Chemistry Students. Here, Students will be trained to improve their factual, conceptual, procedural and metacognitive knowledge. The scientific explanation given in the video contents makes use of the following components: Presentations, chemical structures, figures, tables, images, 3D-animations, white board demonstration, use of molecular models, paper 3D-models, mirrors etc. We gave emphasis to instructional design by leveraging theories based on Malcom Knowels Andragogy, modified Bloom’s taxonomy, the Feynman Technique, ADDIE model, Dick and Carey model, neuro slide design principles etc.


Syllabus

COURSE LAYOUT

We are happy to announce that this course has been very popular among learners. Earlier enrollments for this course: July 2019 - 3591 Jan 2020 - 3224 Learner's Feedback:


"This course is very great and is helpful not only for students but also for all chemistry professors. This course is the best platform for all organic chemistry learners. The language is very easy. So that, each and every student can understand all the concepts easily. Discussion forum is also a best platform for us to ask any query about any concept.

Thank you very much sir for excellent teaching, clearing every concept in organic chemistry from basic and giving assignments to us. Keep it up sir.

Also,thanks to SWAYAM for conducting such type of course for all chemistry learners." ---- Ketaki, One of the topper from the course July-2019.


"The classes are very explanatory and very useful for the PG students and also for the faculty members. I really appreciate the efforts taken by Balaji sir. " ---Seethalakshmi S



"The course content was so relevant and insightful that every individual would definitely benefit hugely from it for their career in chemistry. The classes are very vivid, crystal clear and knowledgeable. I am very fortunate to be part of this course." ---- Ramakrishna S



"Professor Balaji did splendid job and did lots of efforts. Its been 15 days to the course have started and I am taking it right now. This course is beneficial to all as the professor took the course from basics to advance, this make learning very easy & he is very responsive which makes it very convenient." ----- Simran K


"very good nd well qualified professors.

for solving gate, net questions, dis course iz useful. thanku for efforts of all professors". ---- Anonymous




Syllabus

Week 1

Introduction to stereochemistry

Conformational analysis of open chain systems



Week 2

Conformational analysis of cyclic systems

Symmetry elements, Point group analysis

Stereochemical conventions


Week 3

Stereogenicity, Topicity

ORD and CD, Axial halo ketone rule, Octant Rule


Week 4

Stereochemical reactions

Reactions involving stereo centres

Crams Rule, Felkin-Anh model, Prelog rules


Week 5

Aromaticity, Aromatic stabilization energy, Hückel MO, Musulin-Frost diagram

Polycyclic aromatic hydrocarbon (PAH), Polyacenes, Annulene


Week 6

Aromatic Electrophilic substitutions

Aromatic Nucleophilic substitutions

Ipso-cine-tele substitution


Week 7

Reaction dynamics, Hammond postulate

Linear free energy relationship, Hammett equation


Week 8

Yukawa Tsuno equation, Swain-Lupton equation, Grunwald–Winstein equation, Taft equation

Curtin-Hammett principle, Winstein-Holness equation

Carbocation, Part 1: Generation, Structure and Geometry


Week 9

Carbocation, Part 2: Stabilisation of carbocation, Reactions

Carbocation, Rearrangement 1: No Change in carbon skeleton, Change in carbon skeleton

Carbocation, Rearrangement 2: involvement of other electron deficient terminus, Anchimeric assistance


Week 10

Carbanions: pKa and its significance

Carbanions: Hard and Soft Acid and Base principle

Carbanions: Structure, Formation, Stability, Reactivity


Week 11

Carbanion reactions: Acyl Anions, Benzoin condensation, Umpolung-inversion of reactivity

Free radical 1: Formation, Structure, Stability



Week 12

Free radical 2: Stability, Reactivity

Free radical 3: Reactions: Addition, atom abstraction, disproportionation, cyclisation



Week 13

Free radical 4: Reactions: Fenton, Kolbe, Bouveault-Blanc, Giese, Hofmann-Loffler, Birch, Barton-McCombie, Sandmeyer, Barton decarboxylation

Carbene, Nitrene: Generation, Structure, Reactivity



Week 14

Carbonyl addition reaction

Enol and enolate formation and reactions

Enamines formation and reactions



Week 15

Enol ethers formation and reactions, Mukaiyama-Aldol reaction

Sharpless epoxidation, Click reaction, Diels-Alder reaction- Scope and mechanism



Exam


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