Antimicrobial resistance – theory and methods

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  • Welcome to the course
    • This module is basically a welcome to the course were you can find information on the Course structure, the contents you will be learning in the next modules, the grading, and introduction to the instructors and to the teaching material.
  • Module A- Antimicrobial and antimicrobial action
    • Antimicrobials and antimicrobial action ( includes two lectures and one quiz). Here you will learn a lot about antibiotics/ antimicrobials and you will know more about:what they are, where do they come from, what are the major groups and how can we classify them, how do they have an effect, how do they act on the bacterial cells
  • Module B - Antimicrobials and resistance
    • This module containd information about antimicrobials and the development of resistance in bacteria including causes for resistance and their mechanisms, as well as an insight in how resistance disseminates and how it can be selected.
  • Module C- Antimicrobial susceptibility testing
    • This module deals with antimicrobial susceptibility testing in the laboratory: its importance and use, descriptions of the methods and their applications and detailed descriptions of the procedures applied for the main methods.
  • Module D- Interpretation
    • This module gives practical insight on how to interpret antimicrobial susceptibility results.
  • Module E- Quality assurance
    • This module is dedicated to Quality management and Quality assurance (QA/ Quality control (QC) procedures and use of QC strains to assure the qulaity of results of antimicrobial susceptibility testing: importance, elements and principles.
  • Module F- Alternatives to AST- Genome analysis tools
    • As alternative to the phenotypical methods, the researcher might decide to use genotypically based methods to identify genes of interest. in the lectures of this module we present the Resfinder tool which may be used to find resistance mechanisms ( genes and in the future versions also specific point mutations)from Whole genome sequences of bacteria of interest. The second Lecture is a demonstration of the My DB Finder which can be used to identify genes of interest defined by the user from Whole genome sequence data.
  • Module G- specific resistances

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